PTH was significantly higher in osteopenia group with median 15.4 (9.6-27.5) as compared to their healthy counterparts with median 11.0 (6.6-19.1) (p = 0.004), whereas RANKL was significantly higher in the control group with median 34.3 (20.6-66.3) as compared to osteopenia group with median 24.0 (18.5-39.4) (p = 0.001). Here, TNFSF11 is linked to Osteopenia.