The expressions of FXR, SHP, LXRα, LXRβ, CYP7A1, CYP51, and ApoE were downregulated in the NC group, and TLSP treatment reversed their expression levels (Figure 7(a)), which suggests that TLSP ameliorated hyperlipidemia and accelerated cholesterol and bile acid metabolism via the LXR/FXR-SHP/CYP7A1 signaling pathway. This evidence concerns the gene CYP51A1 and hyperlipidemia.