Serous ovarian cancers have almost 100% spontaneous somatic p53 mutations, colon cancers have about 80%, pancreatic cancers have 70%, non-small cell lung adenocarcinomas have about 70%, and triple negative breast cancers have about 60% p53 mutations (Cancer Genome Atlas Network, 2012). The gene discussed is TP53; the disease is malignant colon neoplasm.