The validated exons included all affected CEs in T1D susceptibility genes (LMO7, ITGB3BP, CDK2, and CENPO), two in T2D susceptibility genes (RBM6 and STARD10), and one gene associated with both T1D and T2D (BCAR1) (Fig 4E). Here, ITGB3BP is linked to type 2 diabetes mellitus.