Similarly, if we study the heatmap of DLBCL data set in Fig. 3, we can see gene X02152_at (LDHA), M25753_at (CCNB1), and M16336_s_at (ENO1) are up-regulated (high expression in DLBCL and low expression in FL) and U59309_at (FH) is down-regulated (high expression for FL and low expression for DLBCL). The gene discussed is ENO1; the disease is diffuse large B-cell lymphoma.