Sarcopenia is also caused by mitochondrial disorders including loss of muscle mitochondria, decreased expression of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), which is the main regulator of mitochondriogenesis, mitochondrial DNA mutations, and an increase in mitochondrial reactive oxygen species (ROS) emission [14]. This evidence concerns the gene PPARGC1A and sarcopenia.