MAPK8 and glioblastoma: Our results showed a significant up-regulation in phospho- c-Jun N-terminal kinase (p-JNK) (Figure 8A, see densitometry analysis) and p-p38 (Figure 8B, see densitometry analysis) in glioblastoma TMZ-treated patients compared to the control group (Figure 8A,B, respectively, see densitometry analyses), denoting the continuous involvement of MAPKs in tumorigenesis following chemotherapy.