By comparing patients with inherited thrombophilia (n = 60) with MTHFR polymorphism versus patients with other etiology of CVST (n = 54) significantly increased values for TC (201.48 ± 38.54 mg/dL vs. 188.81± 35.16 mg/dL; p = 0.023), LDLc (115.35 ± 27.47 mg/dL vs. 94.25± 25.44 mg/dL; p = 0.008), tHcy (34.79 ± 34.02 μmol/L vs. 12.23 ± 4.72 μmol/L; p < 0.001), hsCRP (7.12 ± 2.88 mg/L vs. 14.44 ± 16.02 mg/L; p = 0.046) were found in the first group. This evidence concerns the gene MTHFR and Rare hereditary thrombophilia.