CPA1 and pancreatitis: Since then, genetic causes of pancreatitis, calcium-sensing receptor (CASR) in 2003 [14,15,16,17], chymotrypsin C in 2008 (CTRC) [18], claudin-2 (CLDN2) in 2012 [19], carboxypeptidase A1 (CPA1) in 2013 [20], carboxyl ester lipase (CEL) in 2015 [21], chymotrypsin B1 and B2 (CTRB1/CTRB2) in 2017 [22], pancreatic lipase (PNLIP) in 2019 [23], and transient receptor cation channel subfamily V member 6 gene (TRPV6) in 2020 [24] have also been reported to play key roles in the etiology of APR and CP.