IL2 and Zinc deficiency: An experimental human zinc deficiency caused an imbalance between T helper 1 (Th1) cell and T helper 2 (Th2) cell responses by decreasing the production of interferon-γ (IFN-γ) and IL-2 cytokines, both products of Th1, while not affecting the production of IL-4, IL-6, and IL-10 cytokines, products of Th2 [51].