In addition to being thought of as PSFs, GRHL2 and OVOL1/2 have been considered as Mesenchymal-Epithelial Transition (MET)-inducing transcription factors (MET-TFs), as their overexpression in carcinomas is capable of upregulating the expression levels of E-cadherin and/or revert EMT [50,51,52,53,54] as well as other EMT-associated traits, such as anoikis resistance, metabolic reprogramming [55], and immune evasion [56]. The gene discussed is GRHL2; the disease is carcinoma.