FLT3 and acute myeloid leukemia: For binase, the selective cytotoxicity toward cancer cell lines expressing certain oncogenes, namely ras, kit, acute myelogenous leukemia 1 AML1) transcription factor and the eight-twenty one (ETO) corepressor, and FMS-like tyrosine kinase 3 (FLT3), has been previously demonstrated [15,20,22,26,27].