Our findings with respect to the changes of IGFBP-1 and hsCRP during pregnancy are in agreement with the results of previous studies [60,61,62,63] but some discrepancies exist regarding hsCRP, e.g., a study conducted in non-obese pregnant women with GDM detected an elevation in hsCRP along with the gestational age [64]. Here, IGFBP1 is linked to gestational diabetes.