Moreover, MALAT1 knockdown hampered PCa tumorigenesis and progression, as demonstrated by the reduction of cell proliferative, migratory, and invasive capacities in PCa cells and xenografts following MALAT1 depletion [44], hinting at the potential value of MALAT1 in PCa diagnosis [45], prognosis prediction of, and treatment outcome. This evidence concerns the gene MALAT1 and posterior cortical atrophy.