EGFR and neoplasm: However, when compared with the respective congeners without the EGFR-targeting panitumumab, the uptake in tumour was not significantly different; and in both cases, some accumulation in non-targeted organs like liver and spleen had increased about 3–4 fold between 1 to 48 h p.i. Dosimetry studies estimated that the tumour receives the highest dose, and the liver, spleen and pancreas are the non-targeted organs more exposed to radioactivity.