To further determine whether high expression of AnxA2 detected in serum samples of TNBC patients is linked with the phosphorylation of AnxA2 at Tyr23 present in tumor tissues of TNBC patients, the expression of pAnxA2-Y23 were analyzed in tumor tissues of TNBC patients and matched adjacent non-tumorigenic breast tissues by immunoblot analysis. This evidence concerns the gene ANXA2 and neoplasm.