The median expression value of serum AnxA2 was categorized as a threshold to divide the breast cancer patients (n = 162) into two groups: high serum AnxA2 group (>10.11 ng/mL; n = 81) and low AnxA2 (<10.11 ng/mL; n = 81) group. This evidence concerns the gene ANXA2 and breast carcinoma.