On a similar note, Glutamate dehydrogenase 1, when highly expressed, has been a favorable prognostic factor [31,32,43], while Proliferating cell nuclear antigen, playing a crucial role in DNA replication and cell cycle regulation [50,51], is correlated with increasing tumor grade and decreasing patient survival rates when overexpressed [44]. The gene discussed is GLUD1; the disease is neoplasm.