By investigating the six proteins statistically higher in CUSA A-, some of these have demonstrated to be a favorable prognostic marker in GBM such as Glutamate dehydrogenase 1 [31,32,43], while others, when over-expressed, have been associated with unfavorable prognosis in GBM such as Proliferating cell nuclear antigen [44] and synapsin-1 [31,32,45]. Here, SYN1 is linked to glioblastoma.