What is more, patients suffering from obesity with NASH present a decreased number of Faecalibacterium [46], which possesses anti-inflammatory properties due to the production of NF-kB and interleukin-8 (IL-8) inhibitors and acts locally in the colon by means of anti-inflammatory cytokine induction [47]. The gene discussed is CXCL8; the disease is metabolic dysfunction-associated steatohepatitis.