Regarding pleiotropy of DLBCL with other diseases, a European population study found that variant rs10484561 (HLA-DQB1*01:01 ̃DQA1*01:01 ̃DQB1*05:01 extended haplotype, Linkage Disequilibrium (LD) r2 = 1.0) is associated with both DLBCL risk (OR = 1.36; 95% CI = 1.21–1.52; p = 1.40 × 10−7) and FL risk (OR = 1.64; 95% CI = 1.45–1.86; p = 5.0 × 10−15) using independent cohorts [34]. This evidence concerns the gene HLA-DQB1 and diffuse large B-cell lymphoma.