Several other genes and ncRNAs at 8q24, such as POU5F1B (previously thought to be a pseudogene), PRNCR1, CASC11 and CCAT2, have also been shown to be overexpressed in prostate cancer [14,15,16,17] and may also play a role in the development or progression of prostate cancer. The gene discussed is POU5F1B; the disease is Familial prostate cancer.