In dairy cow studies, the expression of CXCL2 and CXCL3 increased when treated with LPS or lipoteichoic acid (LTA), which are derived from major mastitis pathogens such as E. coli and Staphylococcus aureus in bovine, mammary, epithelial cells [53,54]. The gene discussed is CXCL3; the disease is mastitis.