To further demonstrate the involvement of autophagy in the AdoMet response of colon cancer cells, and in particular, the ability of AdoMet to overcome the drug resistance of uL3∆HCT 116p53−/− cells, we evaluated the protein expression levels of Atg7, p62, and LC3B by western blot analysis in both cell lines. This evidence concerns the gene ATG7 and malignant colon neoplasm.