Among the cluster of dysregulated miRNAs in co-culture MCF7 cells, the miR-200 family has been identified as the master key where it has been linked to chemoresistance, tumor metastasis and dormancy by targeting the signaling pathways including Wnt and transforming growth factor β (TGF-β), thus impeding metastasis, cell adhesion and epithelial-to-mesenchymal transition (EMT). The gene discussed is TGFB1; the disease is neoplasm.