An examination of the the Cancer Genome Atlas (TCGA) database reveals that for the squamous cell subset of NSCLC lung squamous cell carcinoma (LUSC), TNF shows a trend as an oncogene, as patients with higher TNF mRNA levels are associated with shorter overall survival (OS), although this correlation does not reach statistical significance (Figure 1A). The gene discussed is TNF; the disease is squamous cell lung carcinoma.