TFAP4 and adrenal cortex carcinoma: Cox regression analysis of PFI identified high TFAP4 expression as a risk factor in ACC (P = .010), KIRP (P = .032), KIRC (P < .001), PRAD (P = .001), LIHC (P < .001), THCA (P = .004) and UCEC (P = .008), while it was a protective factor in GBM (P = .004), LGG (P < .001) and LUSC (P = .017) (Figure 5A).