TFAP4 and adrenal cortex carcinoma: In the OS analysis, Cox regression identified that high TFAP4 expression was a risk factor for ACC (P = .049), KIRC (P < .001), KIRP (P < .001), SKCM (P = .026) and LIHC (P < .001); however, it appeared to be a protective factor in UVM (P = .009), READ (P = .012), STAD (P = .046) and LGG (P = .008), as shown in Figure 3A and Table 1.