RPGR and retinitis pigmentosa 1: ,30,33–35 Finally, some RPGR variants in exons 1 to 14 were reported in patients with RP presenting progressive hearing loss, sinusitis, and chronic recurrent respiratory tract infections,36–38 in line with the more widespread expression of the RPGR1–19 isoform and its essential ciliary function in other organs apart from retina.39