Results have shown that a cohort of immune cells existed in lung adenocarcinoma, such as B cells naïve, B cells memory, plasma cells, T cells CD8, T cells CD4 naïve, T cells CD4 memory resting, T cells CD4 memory activated, et al. Among these immune cells, we have found that in CD44 high and CD44 low lung adenocarcinoma, there was a significant difference in the amount of T cells CD4 memory resting and mast cells resting (Fig. 2a). The gene discussed is CD44; the disease is lung adenocarcinoma.