Compared with source tumors, BC organoids #25 and #30 showed different SCNV levels in driver genes such as the oncogenes ERBB4 (#25), NRAS (#25), ERBB2 (#30), and XPOI (#30), and the tumor suppressor genes APC (#25), FAT1 (#25), and PTEN (#30). This evidence concerns the gene PTEN and breast cancer.