INSR and benign prostatic hyperplasia: Since insulin receptors control wing plasticity in BPH [11], three miRNAs, Nlu-miR-14-3p, Nlu-miR-9a-5p and Nlu-miR-315-5p, which are predicted to target the insulin receptors, were selected to confirm the interaction between miRNAs and target genes in dual luciferase reporter assays in vitro.