LPP and neoplasm: Lipoma preferred partner (LPP) is a member of the zyxin family of proteins, whose main function is to regulate cytoskeletal organization, cell movement, and mechanical sensitivity.[11] Recent findings have revealed that LPP plays an important role in tumor cell migration, invasion, and metastasis.[11] LPP has the ability to enter the nucleus and localize to focal adhesion, and has been reported to promote the formation of invadopodia.[11]