IL6R and COVID-19: Since only patients with severe COVID-19 have access to anti-inflammatory therapy, more patients in the group of high-flow oxygen support were treated with immunomodulatory therapy like anti-IL-6R therapy (62.2% vs 12.2%; p<0.001) or corticosteroids pulses (28.1% vs 5.1%; p <0.001), but this difference is due to a selection bias of the patients that were more severely ill.