CD27 and infection: ATAC-seq reads revealed differential accessibility at several loci (Fig 5C) with CD27+ memory like NK cells showing increased accessibility for memory and stem cell signatures (Fig 5D) on the other hand non-memory CD27- NK cells demonstrated chromatin opening at loci associated with effector T cell and mature HSC signatures (Fig 5D) corroborating our transcriptomics analysis (Figs 2B, 3A–3N and 4A–4F) that CD27+ NK cells, probed a month post infection, possess memory and stem cell features.