A number of interesting target genes were highlighted during the microarray analysis in SKOV-3 cells following knockdown of TLR4 associated with metastasis, angiogenesis, EMT/differentiation and circulating tumour cell (CTC) biology including CD44, HER2, PI3K, MMP13, members of the claudin, cadherin, integrin and laminin family and various olfactory receptors (ORs). The gene discussed is CDH17; the disease is neoplasm.