Of the target 29 plasma proteins to be measured, 15, including arginase and iNOS, were detected in CRC patients and healthy donors, and the remaining 14 proteins (IL-1b, IL-2, IL-4, IL-5, IL-6, IL-7, IL-10, IL-12p70, IL-13, IL-15, IL-17, MIP-1a, IFN-γ and G-CSF) were excluded from analysis because their value = 0 or NA for > 10 subjects, or whose 75th percentile of value was < 10 subjects. Here, IL6 is linked to colorectal carcinoma.