At day 8 after induction of anti-GBM nephritis, there was no significant difference in albuminuria, blood urea nitrogen (BUN), glomerulosclerosis scores, glomerular C3 staining, CD4+ T cell or macrophage infiltration, in control versus podFcRn KO (Fig 4A–4F, n = 10 control and n = 10 PodFcRn KO mice). This evidence concerns the gene C3 and glomerulosclerosis.