NPHS2 and glomerulonephritis: In order to determine whether podocyte-specific knockout of FcRn would protect against induction of glomerulonephritis, we generated podocyte-specific FcRn KO (podFcRn KO) mice by crossing podocin-Cre mice with FcRn floxed mice to create FcRn fl/fl:Podocin-Cre/+ mice (Fig 3) as previously described [37].