On the other hand and in agreement with USP22 KO HT‐29, USP22 KO Jurkat ALL were not sensitized for TB‐induced cell death, compared to control Jurkat (Fig EV1G–I), similar as USP22 KO acute promyelocytic leukemia (APL) NB4 cells (Appendix Fig S3A and B). Here, USP22 is linked to acute promyelocytic leukemia.