MMP11 and hepatocellular carcinoma: Also, Wang et al., 2018 reported that after potential confounders adjustment, subjects with combined CT and TT of MMP-11 rs738791 polymorphism had a 1.389-fold- ( %95 CI: 1.004-1.921; p < 0.05) higher risk of HCC development compared to those with homozygotes C/C.