LEPR and hepatocellular carcinoma: In the current study, when LEPR rs1137101 GA and AA genotypes were compared with the wild type (GG) of LEPR Gln223Arg, it was found that a significant difference in LEPR rs1137101 GA genotype between subjects with and without HCC and no difference was reported in the LEPR rs1137101 AA genotype between subjects with and without HCC.