While many laminopathies are associated with mutations in LMNA gene (Schreiber & Kennedy, 2013), only two have been associated with alterations in lamin B: the autosomal dominant leukodystrophy (Padiath, 2019) and the acquired partial lipodystrophy (Hegele et al, 2006) caused by LMNB1 and LMNB2 mutations, respectively. This evidence concerns the gene LMNB1 and laminopathy.