Strikingly, two cellular functions in which lamin B plays a critical role, RNA nuclear exportation (Gasset‐Rosa et al, 2017) and nuclear pore complex organization (Grima et al, 2017), are altered in Huntington’s disease (HD), an autosomal dominant neurodegenerative disorder caused by an inherited CAG repeat expansion in the exon 1 of the huntingtin (htt) gene (HDCRG, 1993). The gene discussed is HTT; the disease is Huntington disease.