In contrast to other studies showing that some altered mechanisms, such as transcriptomic dysregulation, are dependent on the CAG repeat length (Langfelder et al, 2016), we did not observe a correlation between the number of CAG repeats and lamin B1 protein levels in the putamen, hippocampus, and cortex of HD patients (Appendix Fig S2). Here, LMNB1 is linked to Huntington disease.