In agreement with our results: (i) Nuclear morphology alterations in autosomal dominant leukodystrophy brain cells have been related to increased lamin B1 levels (Ferrera et al, 2014), and (ii) by using lamin B1 as a marker, nuclear envelope abnormalities have been shown in the brain of HD patients and mouse models (Gasset‐Rosa et al, 2017). Here, LMNB1 is linked to Huntington disease.