MDSCs are recruited to the TME by way of CXCR2 ligands CXCL1, CXCL2, CXCL3, and CXCL5,36 which we found to be downregulated in the spontaneous MISIIR ovarian tumors following class I HDAC inhibition, suggesting ENT might impair accumulation of MDSCs. Here, CXCR2 is linked to ovarian neoplasm.