MMP8 and type 1 diabetes mellitus: Salvi et al. (Salvi, Kandylaki, Troendle, Persson, & Lang, 2005) during a period of experimental gingivitis in subjects with and without T1D, observed a higher and quicker inflammatory response in the T1D group while a secondary analysis of the same group (Salvi et al., 2010) showed significantly higher GCF levels of Il‐1β and MMP‐8 for the T1D subjects.