There were a few reports on the elevated expression of NSUN2 in a range of cancer, including oral (Okamoto et al., 2012), head and neck (Lu et al., 2018), colorectal (Okamoto et al., 2012), breast (Frye et al., 2010; Yi et al., 2017), ovarian (Yang J. C. et al., 2017), and GI cancers (Okamoto et al., 2012), which was consistent with our bioinformatics analysis. The gene discussed is NSUN2; the disease is cancer.