Xie et al. (41) showed that inhibiting FN1-SRC proto-oncogene, non-receptor tyrosine kinase/protein tyrosine kinase 2-guanosine triphosphatase (GTPase) signaling could inhibit CC metastasis, and Cai et al. (42) reported that FN1 depletion could inhibit colorectal carcinogenesis by suppressing proliferation, migration, and invasion. The gene discussed is NTRK1; the disease is medical procedure.