CCL-2 secretion was enhanced in T1D/AIT in IL1β- stimulated monocytes and after IL1β/1,25(OH)2D3 co-stimulation [IL1βT1D/AIT vs HC p = 0.02; IL1β/1,25(OH)2D3 T1D/AIT vs HC p = 0.001] compared to HC. This evidence concerns the gene IL1B and type 1 diabetes mellitus.