Group-wise comparison between AD/AIT and HC revealed increased CCL-2 secretion after IL1β/1,25(OH)2D3 co-stimulation [IL1β/1,25(OH)2D3 AD/AIT vs HC p = 0.02] and in IL1β-inflammatory stimulated monocytes by a trend (IL1βAD/AIT vs HC p = 0.06). The gene discussed is CCL2; the disease is Alzheimer disease.