DPP4 and heart failure: Mixed results from CVOTs and meta-analyses suggesting a potential drug-specific effect of DPP-4 inhibitors to impact heart failure in people with T2DM, emphasizes the need for future clinical studies to compare different DPP-4 inhibitors head-to-head, while assessing relevant heart failure endpoints in subjects with T2DM and either HFpEF or HFrEF.