In agreement with our results, previous studies have reported that the compensatory activation of autophagy was induced in breast carcinoma cells and cardiomyocytes and was associated with p62-related NFE2L2 activation and inhibition of proteasome activity (Ding et al., 2007; Su and Wang, 2011; Ryoo et al., 2015). This evidence concerns the gene NFE2L2 and breast carcinoma.