SIGMAR1 and hepatocellular carcinoma: Accordingly, evidence on the role played in viral replication by host Sig-1R in cultured hepatoma cells (not the primary cell target of SARS-CoV-2) infected with HCV (a +ssRNA virus, but not SARS-CoV-2) in no case imply proven mechanistic correlates against SARS-CoV-2 on its natural target cells.