Mucopolysaccharidosis type VI (MPS VI, Maroteaux‐Lamy syndrome) is an autosomal recessive lysosomal storage disorder caused by a deficiency of the N‐acetylgalactosamine 4 sulfatase enzyme (also known as arylsulfatase B or ASB), which results in the accumulation of the glycosaminoglycan (GAG) dermatan sulfate (DS) in different tissues of the body.1 The gene discussed is ARSB; the disease is lysosomal storage disease.