Functional enrichment analysis indicated that the genes in the key module were mainly enriched in leukocyte migration, positive chemotaxis, and cell chemotaxis, whereas KEGG analysis indicated that these genes were significantly enriched in pathways associated with bladder cancer, proteoglycans in cancer, and AGE-RAGE signaling pathway in diabetic complications (Table 1). Here, RENBP is linked to urinary bladder carcinoma.