In addition, the KEGG pathway enrichment analysis indicated that our identified DEOGs were not only significantly associated with the prognosis of pancreatic cancer, but also played a critical role in numerous other tumors, including bladder cancer, hepatocellular carcinoma, prostate cancer, melanoma, and colorectal cancer, prompting us to further explore the potential role of OS genes in other tumors. This evidence concerns the gene MID1 and colorectal cancer.