IL17A and periodontitis: However, this does not seem to be the case in periodontitis, since the few studies that use P. gingivalis for disease modeling show dual functions for the main cytokines with inflammatory functions in autoimmunity, eg. the hyperproduction of IL-17 of great interest in the pathogenesis of periodontitis due to its involvement both in the inflammatory response and in the protective immunity against microorganisms (233).